Objective: To evaluate the effect of chlorhexidine dressing in comparison with acetic acid dressing in the treatment of wounds infected with Pseudomonas aeruginosa. Materials and Methods: Sixty eight patients diagnosed of Grade 1 or Grade 2 ulcer, positive for P. aeruginosa were grouped and treated with 1% acetic acid and 0.05% chlorhexidine group as daily dressing material. Wound swab was collected on days 0 and day 7. Bacterial load on both the days were compared and scored as no growth, mild growth, moderate growth and severe growth based on gram staining, number colonies on culture plate. Results: In acetic acid treatment group, majority of the patients who had mild growth of bacterial load on day 0 (80%) had no growth on day 7, followed by 72.8% who had severe growth on day 0 had no growth and mild growth (36.4% each). Whereas in chlorhexidine group, there was no growth of P. aeruginosa as observed in 23 patients on day 0. Overall, the efficacy of topical application of chlorhexidine for its antiseptic activity was comparable with acetic acid in wounds infected with P. aeruginosa in diabetes mellitus, Peripheral Vascular Occlusive Disease (PVOD), varicose vein and hypertension cases. Conclusion: In conclusion, the results of the present study depict that topical application of chlorhexidine on P. aeruginosa infected wound was at par with acetic acid in terms of its antiseptic activity.
COMPARITIVE ANALYSIS OF ACETIC ACID AND CHLORHEXIDINE DRESSINGS ON WOUNDS INFECTED WITH PSEUDOMONAS AERUGINOSA, Suhas Gowda, Bhagavan K R, INTERNATIONAL JOURNAL OF ADVANCED MEDICINE : Volume-4 | Issue-4 | July-2020